Updated in 2/28/2011 11:28:34 AM      Viewed: 942 times      (Journal Article)
Journal of the American Academy of Child and Adolescent Psychiatry 49 (6): 539-51 (2010)

Basal ganglia shapes predict social, communication, and motor dysfunctions in boys with autism spectrum disorder

A Qiu , M Adler , D Crocetti , MI Miller , SH Mostofsky
OBJECTIVE: Basal ganglia abnormalities have been suggested as contributing to motor, social, and communicative impairments in autism spectrum disorder (ASD). Volumetric analyses offer limited ability to detect localized differences in basal ganglia structure. Our objective was to investigate basal ganglia shape abnormalities and their association with behavioral features of ASD, which may involve multiple frontal-subcortical circuits.
ISSN: 0890-8567