KL Lee Publications
Last updated in Jun 26, 2011 5:10 PM Number of Items: 8 Viewed: 1093 times
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Keywords:
Stem Cells, Pluripotency, Differentiation, Activin, Nodal
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1.

Graded Nodal/Activin Signaling Titrates Conversion of Quantitative Phospho-Smad2 Levels into Qualitative Embryonic Stem Cell Fate Decisions

PLoS genetics , Volume 7 , Issue 6 (2011)
Kian Leong Lee , Sandy Keat Lim , Yuriy Lvovich Orlov , Le Yau Yit , Henry Yang , Lay Teng Ang , Lorenz Poellinger , Bing Lim
2.

Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state.

Stem cells (Dayton, Ohio) , Volume 28 , Issue 2 (2010)
Fredrik Lanner , Kian Leong Lee , Marcus Sohl , Katarina Holmborn , Henry Yang , Johannes Wilbertz , Lorenz Poellinger , Janet Rossant , Filip Farnebo
3.

Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells.

PloS one , Volume 4 , Issue 1 (2009)
Marcela Guzman-Ayala , Kian Leong Lee , Konstantinos J Mavrakis , Paraskevi Goggolidou , Dominic P Norris , Vasso Episkopou
4.

Generating specificity and diversity in the transcriptional response to hypoxia.

Nature reviews. Genetics , Volume 10 , Issue 12 (2009)
Urban Lendahl , Kian Leong Lee , Henry Yang , Lorenz Poellinger
5.

Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling.

The Journal of biological chemistry , Volume 282 , Issue 28 (2007)
Yoshiko Nagano , Konstantinos J Mavrakis , Kian Leong Lee , Tomoko Fujii , Daizo Koinuma , Hitoshi Sase , Keiko Yuki , Kazunobu Isogaya , Masao Saitoh , Takeshi Imamura , Vasso Episkopou , Kohei Miyazono , Keiji Miyazawa
6.

Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover.

PLoS biology , Volume 5 , Issue 3 (2007)
Konstantinos J Mavrakis , Rebecca L Andrew , Kian Leong Lee , Chariklia Petropoulou , James E Dixon , Naveenan Navaratnam , Dominic P Norris , Vasso Episkopou
7.

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells.

Experimental cell research , Volume 316 , Issue 9 (2010)
Heather Main , Kian Leong Lee , Henry Yang , Saija Haapa-Paananen , Henrik Edgren , Shaobo Jin , Cecilia Sahlgren , Olli Kallioniemi , Lorenz Poellinger , Bing Lim , Urban Lendahl
8.

Down-regulation of Myc is essential for terminal erythroid maturation.

The Journal of biological chemistry , Volume 285 , Issue 51 (2010)
Senthil Raja Jayapal , Kian Leong Lee , Peng Ji , Philipp Kaldis , Bing Lim , Harvey F Lodish